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TitleDisrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase.
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 104, Page 12282-12287, Year 2007
Publish dateJun 7, 2007 (structure data deposition date)
AuthorsLujan, S.A. / Guogas, L.M. / Ragonese, H. / Matson, S.W. / Redinbo, M.R.
External linksProc. Natl. Acad. Sci. Usa / PubMed:17630285
MethodsX-ray diffraction
Resolution2.42 - 3 Å
Structure data

PDB-2q7t:
Crystal Structure of the F plasmid TraI Relaxase Domain with the Scissile Thymidine Base
Method: X-RAY DIFFRACTION / Resolution: 2.42 Å

PDB-2q7u:
Crystal Structure of the F plasmid TraI Relaxase Domain with the Scissile Thymidine Base and Imidodiphosphate
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-TMP:
THYMIDINE-5'-PHOSPHATE

ChemComp-HOH:
WATER

ChemComp-PON:
IMIDO DIPHOSPHATE

Source
  • escherichia coli (E. coli)
KeywordsHYDROLASE / relaxase / conjugation / Alternative initiation / ATP-binding / DNA-binding / Helicase / Nucleotide-binding / Plasmid

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