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Structure paper

TitleIntegration of inositol phosphate signaling pathways via human ITPK1.
Journal, issue, pagesJ. Biol. Chem., Vol. 282, Page 28117-28125, Year 2007
Publish dateJun 6, 2007 (structure data deposition date)
AuthorsChamberlain, P.P. / Qian, X. / Stiles, A.R. / Cho, J. / Jones, D.H. / Lesley, S.A. / Grabau, E.A. / Shears, S.B. / Spraggon, G.
External linksJ. Biol. Chem. / PubMed:17616525
MethodsX-ray diffraction
Resolution1.6 - 1.8 Å
Structure data

PDB-2q7d:
Crystal Structure of Human Inositol 1,3,4-Trisphosphate 5/6-kinase (ITPK1) in complex with AMPPNP and Mn2+
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-2qb5:
Crystal Structure of Human Inositol 1,3,4-Trisphosphate 5/6-Kinase (ITPK1) in Complex with ADP and Mn2+
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

ChemComp-HOH:
WATER

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / INOSITOL / INOSITOL KINASE / KINASE / ITPK1 / INOSITOL 1 / 3 / 4-5/6-KINASE / PHOSPHATE / INOSITOL PHOSPHATE / INOSITOLPHOSPHATE / POLYPHOSPHATE

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