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TitleSubstrate Specificity Profiling and Identification of a New Class of Inhibitor for the Major Protease of the SARS Coronavirus.
Journal, issue, pagesBiochemistry, Vol. 46, Page 8744-8752, Year 2007
Publish dateJan 27, 2007 (structure data deposition date)
AuthorsGoetz, D.H. / Choe, Y. / Hansell, E. / Chen, Y.T. / McDowell, M. / Jonsson, C.B. / Roush, W.R. / McKerrow, J. / Craik, C.S.
External linksBiochemistry / PubMed:17605471
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-2op9:
Substrate Specificity Profiling and Identification of a New Class of Inhibitor for the Major Protease of the SARS Coronavirus
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-WR1:
NALPHA-[(BENZYLOXY)CARBONYL]-N-[(1R)-4-HYDROXY-1-METHYL-2-OXOBUTYL]-L-PHENYLALANINAMIDE

ChemComp-HOH:
WATER

Source
  • sars coronavirus
KeywordsHYDROLASE / SARS / 3Clpro / proteinase / protease

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