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Structure paper

TitlePGH2 degradation pathway catalyzed by GSH-heme complex bound microsomal prostaglandin E2 synthase type 2: the first example of a dual-function enzyme.
Journal, issue, pagesBiochemistry, Vol. 46, Page 8414-8424, Year 2007
Publish dateMar 28, 2007 (structure data deposition date)
AuthorsYamada, T. / Takusagawa, F.
External linksBiochemistry / PubMed:17585783
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-2pbj:
GSH-heme bound microsomal prostaglandin E synthase
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-GSH:
GLUTATHIONE

ChemComp-HOH:
WATER

Source
  • macaca fascicularis (crab-eating macaque)
KeywordsISOMERASE / LYASE / Prostaglandin E synthase / GSH-heme bound enzyme / Dual function enzyme

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