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TitleTumour Prevention by a Single Antibody Domain Targeting the Interaction of Signal Transduction Proteins with Ras.
Journal, issue, pagesEmbo J., Vol. 26, Page 3250-, Year 2007
Publish dateApr 27, 2007 (structure data deposition date)
AuthorsTanaka, T. / Williams, R.L. / Rabbitts, T.H.
External linksEmbo J. / PubMed:17568777
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-2uzi:
Crystal structure of HRAS(G12V) - anti-RAS Fv complex
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN/IMMUNE SYSTEM / SIGNAL TRANSDUCTION / IMMUNOGLOBULIN DOMAIN / MEMBRANE / ANTIBODY / ONCOGENE / PALMITATE / INTRABODY / DISEASE MUTATION / NUCLEOTIDE-BINDING / PROTO-ONCOGENE / CANCER THERAPY / GOLGI APPARATUS / PRENYLATION / METHYLATION / LIPOPROTEIN / GTP- BINDING / SIGNALING PROTEIN-IMMUNE SYSTEM complex

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