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TitleStructure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in a quaternary complex with a magnesium ion, NADPH and the antimalarial drug fosmidomycin
Journal, issue, pagesActa Crystallogr. ,Sect. F, Vol. 63, Page 466-470, Year 2007
Publish dateMar 1, 2007 (structure data deposition date)
AuthorsYajima, S. / Hara, K. / Iino, D. / Sasaki, Y. / Kuzuyama, T. / Ohsawa, K. / Seto, H.
External linksActa Crystallogr. ,Sect. F / PubMed:17554164
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-2egh:
Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase complexed with a magnesium ion, NADPH and fosmidomycin
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-FOM:
3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID / antibiotic*YM

ChemComp-NDP:
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-HOH:
WATER

Source
  • escherichia coli str. k12 substr. (bacteria)
KeywordsOXIDOREDUCTASE / Protein-inhibitor complex

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