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TitleStructural and functional consequences of single amino acid substitutions in the pyrimidine base binding pocket of Escherichia coli CMP kinase.
Journal, issue, pagesFebs J., Vol. 274, Page 3363-3373, Year 2007
Publish dateDec 16, 2005 (structure data deposition date)
AuthorsOfiteru, A. / Bucurenci, N. / Alexov, E. / Bertrand, T. / Briozzo, P. / Munier-Lehmann, H. / Gilles, A.M.
External linksFebs J. / PubMed:17542990
MethodsX-ray diffraction
Resolution1.9 - 2.8 Å
Structure data

PDB-2fem:
Mutant R188M of the Cytidine Monophosphate Kinase From E. Coli
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2feo:
Mutant R188M of The Cytidine Monophosphate Kinase from E. coli complexed with dCMP
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-DC:
2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE / dCMP*YM

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsSIGNALING PROTEIN / TRANSFERASE / NUCLEOTIDE MONOPHOSPHATE KINASE; TRANSFERASE

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