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TitleInhibition of Caspase-2 by a Designed Ankyrin Repeat Protein: Specificity, Structure, and Inhibition Mechanism.
Journal, issue, pagesStructure, Vol. 15, Page 625-636, Year 2007
Publish dateMar 7, 2007 (structure data deposition date)
AuthorsSchweizer, A. / Roschitzki-Voser, H. / Amstutz, P. / Briand, C. / Gulotti-Georgieva, M. / Prenosil, E. / Binz, H.K. / Capitani, G. / Baici, A. / Pluckthun, A. / Grutter, M.G.
External linksStructure / PubMed:17502107
MethodsX-ray diffraction
Resolution3.24 Å
Structure data

PDB-2p2c:
Inhibition of caspase-2 by a designed ankyrin repeat protein (DARPin)
Method: X-RAY DIFFRACTION / Resolution: 3.24 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / apoptosis / caspase / caspase-2 / inhibition / protein design / protein libraries / designed ankyrin repeat proteins / ribosome display

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