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TitleHydrogen Bonding of 7,8-Dihydro-8-Oxodeoxyguanosine with a Charged Residue in the Little Finger Domain Determines Miscoding Events in Sulfolobus Solfataricus DNA Polymerase Dpo4.
Journal, issue, pagesJ. Biol. Chem., Vol. 282, Page 19831-, Year 2007
Publish dateMar 13, 2007 (structure data deposition date)
AuthorsEoff, R.L. / Irimia, A. / Angel, K.C. / Egli, M. / Guengerich, F.P.
External linksJ. Biol. Chem. / PubMed:17468100
MethodsX-ray diffraction
Resolution2.09 - 2.9 Å
Structure data

PDB-2uvr:
Crystal structures of mutant Dpo4 DNA polymerases with 8-oxoG containing DNA template-primer constructs
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-2uvu:
Crystal structures of mutant Dpo4 DNA polymerases with 8-oxoG containing DNA template-primer constructs
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-2uvv:
Crystal structures of mutant Dpo4 DNA polymerases with 8-oxoG containing DNA template-primer constructs
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-2uvw:
Crystal structures of mutant Dpo4 DNA polymerases with 8-oxoG containing DNA template-primer constructs
Method: X-RAY DIFFRACTION / Resolution: 2.09 Å

Chemicals

ChemComp-DGT:
2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • sulfolobus solfataricus (archaea)
KeywordsTRANSFERASE / DNA-DIRECTED DNA POLYMERASE / P2 DNA POLYMERASE IV / NUCLEOTIDYLTRANSFERASE / 7 / MAGNESIUM / DNA DAMAGE / DNA REPAIR / DNA-BINDING / TRANSLESION DNA POLYMERASE / METAL-BINDING / 8-DIHYDRO-8- OXODEOXYGUANOSINE / METAL- BINDING / MUTATOR PROTEIN / DNA REPLICATION

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