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Structure paper

TitleStructural and energetic aspects of Grb2-SH2 domain-swapping.
Journal, issue, pagesArch. Biochem. Biophys., Vol. 462, Page 47-53, Year 2007
Publish dateMay 23, 2006 (structure data deposition date)
AuthorsBenfield, A.P. / Whiddon, B.B. / Clements, J.H. / Martin, S.F.
External linksArch. Biochem. Biophys. / PubMed:17466257
MethodsX-ray diffraction
Resolution1.9 - 3.25 Å
Structure data

PDB-2h46:
Native domain-swapped dimer crystal structure of the Grb2 SH2 domain
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2h5k:
Crystal Structure of Complex Between the Domain-Swapped Dimeric Grb2 SH2 Domain and Shc-Derived Ligand, Ac-NH-pTyr-Val-Asn-NH2
Method: X-RAY DIFFRACTION / Resolution: 3.25 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-CAC:
CACODYLATE ION

Source
  • homo sapiens (human)
KeywordsHORMONE/GROWTH FACTOR / helix-sheet-helix / HORMONE-GROWTH FACTOR COMPLEX / Domain-swapping / protein-phosphopeptide complex

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