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Structure paper

TitleMolecular architecture of DesV from Streptomyces venezuelae: A PLP-dependent transaminase involved in the biosynthesis of the unusual sugar desosamine.
Journal, issue, pagesProtein Sci., Vol. 16, Page 887-896, Year 2007
Publish dateJan 5, 2007 (structure data deposition date)
AuthorsBurgie, E.S. / Thoden, J.B. / Holden, H.M.
External linksProtein Sci. / PubMed:17456741
MethodsX-ray diffraction
Resolution2.05 Å
Structure data

PDB-2oga:
X-ray crystal structure of S. venezuelae DesV in complex with ketimine intermediate
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

PDB-2oge:
x-ray structure of S. venezuelae DesV in its internal aldimine form
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PGU:
N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-glutamic acid

ChemComp-HOH:
WATER

Source
  • streptomyces venezuelae (bacteria)
KeywordsHYDROLASE / PLP-dependent enzyme / desosamine / transaminase / deoxysugars / antibiotics / TRANSFERASE / macrolide antibiotics

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