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Structure paper

TitleSmall molecule inhibitors of a glycoside hydrolase attenuate inducible AmpC-mediated beta-lactam resistance.
Journal, issue, pagesJ. Biol. Chem., Vol. 282, Page 21382-21391, Year 2007
Publish dateFeb 20, 2007 (structure data deposition date)
AuthorsStubbs, K.A. / Balcewich, M. / Mark, B.L. / Vocadlo, D.J.
External linksJ. Biol. Chem. / PubMed:17439950
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-2oxn:
Vibrio cholerae family 3 glycoside hydrolase (NagZ) in complex with PUGNAc
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-OAN:
O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE / inhibitor*YM

ChemComp-HOH:
WATER

Source
  • vibrio cholerae (bacteria)
KeywordsHYDROLASE / TIM-barrel

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