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TitleThe structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation.
Journal, issue, pagesJ. Biol. Chem., Vol. 282, Page 18182-18189, Year 2007
Publish dateDec 9, 2006 (structure data deposition date)
AuthorsCendron, L. / Berni, R. / Folli, C. / Ramazzina, I. / Percudani, R. / Zanotti, G.
External linksJ. Biol. Chem. / PubMed:17428786
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-2o70:
Structure of OHCU decarboxylase from zebrafish
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-2o73:
Structure of OHCU decarboxylase in complex with allantoin
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-2o74:
Structure of OHCU decarboxylase in complex with guanine
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-2AL:
1-(2,5-DIOXO-2,5-DIHYDRO-1H-IMIDAZOL-4-YL)UREA

ChemComp-GUN:
GUANINE

Source
  • danio rerio (zebrafish)
KeywordsLYASE / Uric acid / decarboxylation / 5-hydroxyisourate / allantoin / OHCU / 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline / HIU

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