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-Structure paper
Title | 1,3-Disubstituted 4-Aminopiperidines as Useful Tools in the Optimization of the 2-Aminobenzo[A]Quinolizine Dipeptidyl Peptidase Iv Inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 17, Page 2966-, Year 2007 |
Publish date | Feb 28, 2007 (structure data deposition date) |
Authors | Lubbers, T. / Bohringer, M. / Gobbi, L. / Hennig, M. / Hunziker, D. / Kuhn, B. / Loffler, B. / Mattei, P. / Narquizian, R. / Peters, J. ...Lubbers, T. / Bohringer, M. / Gobbi, L. / Hennig, M. / Hunziker, D. / Kuhn, B. / Loffler, B. / Mattei, P. / Narquizian, R. / Peters, J. / Ruff, Y. / Wessel, H.P. / Wyss, P. |
External links | Bioorg. Med. Chem. Lett. / PubMed:17418568 |
Methods | X-ray diffraction |
Resolution | 2.8 Å |
Structure data | PDB-2jid: |
Chemicals | ChemComp-NAG: ChemComp-GVB: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / DIABETES TYPE II / DIPEPTIDYL PEPTIDASE / PROTEASE / MEMBRANE / B-PROPELLER / STRUCTURE BASED DESIGN / GLYCOPROTEIN / SIGNAL-ANCHOR / TRANSMEMBRANE / HYDROLASE FOLD / AMINOPEPTIDASE / SERINE PROTEASE |