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Structure paper

TitleStructure, substrate recognition and reactivity of Leishmania major mevalonate kinase.
Journal, issue, pagesBmc Struct. Biol., Vol. 7, Page 20-20, Year 2007
Publish dateJun 26, 2006 (structure data deposition date)
AuthorsSgraja, T. / Smith, T.K. / Hunter, W.N.
External linksBmc Struct. Biol. / PubMed:17397541
MethodsX-ray diffraction
Resolution1.75 - 2 Å
Structure data

PDB-2hfs:
Crystal structure of L. major mevalonate kinase
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-2hfu:
Crystal structure of L. major mevalonate kinase in complex with R-mevalonate
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-MEV:
(R)-MEVALONATE

Source
  • leishmania major (eukaryote)
KeywordsTRANSFERASE / GHMP kinase / mevalonate kinase / Trypanosomatid parasite

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