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Structure paper

TitleA Tick Protein with a Modified Kunitz Fold Inhibits Human Tryptase.
Journal, issue, pagesJ. Mol. Biol., Vol. 368, Page 1172-, Year 2007
Publish dateMar 8, 2007 (structure data deposition date)
AuthorsPaesen, G.C. / Siebold, C. / Harlos, K. / Peacey, M.F. / Nuttall, P.A. / Stuart, D.I.
External linksJ. Mol. Biol. / PubMed:17391695
MethodsX-ray diffraction
Resolution1.15 - 1.4 Å
Structure data

PDB-2uux:
Structure of the tryptase inhibitor TdPI from a tick
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-2uuy:
Structure of a tick tryptase inhibitor in complex with bovine trypsin
Method: X-RAY DIFFRACTION / Resolution: 1.15 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-CA:
Unknown entry

ChemComp-CL:
Unknown entry

Source
  • rhipicephalus appendiculatus (arthropod)
  • bos taurus (domestic cattle)
KeywordsINHIBITOR / TRYPTASE INHIBITOR / HYDROLASE / CALCIUM / ZYMOGEN / PROTEASE / DIGESTION / METAL-BINDING / SERINE PROTEASE

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