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TitleStructural Mechanism for the Fine-tuning of CcpA Function by The Small Molecule Effectors Glucose 6-Phosphate and Fructose 1,6-Bisphosphate.
Journal, issue, pagesJ. Mol. Biol., Vol. 368, Page 1042-1050, Year 2007
Publish dateNov 25, 2006 (structure data deposition date)
AuthorsSchumacher, M.A. / Seidel, G. / Hillen, W. / Brennan, R.G.
External linksJ. Mol. Biol. / PubMed:17376479
MethodsX-ray diffraction
Resolution2.5 - 3.17 Å
Structure data

PDB-2nzu:
Structural mechanism for the fine-tuning of CcpA function by the small molecule effectors G6P and FBP
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-2nzv:
Structural mechanism for the fine-tuning of CcpA function by the small molecule effectors G6P and FBP
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-2oen:
Structural mechanism for the fine-tuning of CcpA function by the small molecule effectors glucose-6-phosphate and fructose-1,6-bisphosphate
Method: X-RAY DIFFRACTION / Resolution: 3.17 Å

Chemicals

ChemComp-BG6:
6-O-phosphono-beta-D-glucopyranose

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-FBP:
1,6-di-O-phosphono-beta-D-fructofuranose

Source
  • bacillus megaterium (bacteria)
KeywordsTRANSCRIPTION / CcpA / CCR / HPr-Ser46-P / glucose-6-phosphate / adjunct corepressor / LacI-GalR / HPrser46-p / fructose-bis-phosphate / hpr / crh / protein-dna

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