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-Structure paper
Title | Discovery of potent, selective, orally active, nonpeptide inhibitors of human mast cell chymase. |
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Journal, issue, pages | J. Med. Chem., Vol. 50, Page 1727-1730, Year 2007 |
Publish date | Jul 31, 2006 (structure data deposition date) |
![]() | Greco, M.N. / Hawkins, M.J. / Powell, E.T. / Almond, H.R. / de Garavilla, L. / Hall, J. / Minor, L.K. / Wang, Y. / Corcoran, T.W. / Di Cera, E. ...Greco, M.N. / Hawkins, M.J. / Powell, E.T. / Almond, H.R. / de Garavilla, L. / Hall, J. / Minor, L.K. / Wang, Y. / Corcoran, T.W. / Di Cera, E. / Cantwell, A.M. / Savvides, S.N. / Damiano, B.P. / Maryanoff, B.E. |
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Methods | X-ray diffraction |
Resolution | 2.6 Å |
Structure data | ![]() PDB-2hvx: |
Chemicals | ![]() ChemComp-DRX: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / serine protease |