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Structure paper

TitleMechanisms of Cholinesterase Inhibition by Inorganic Mercury.
Journal, issue, pagesFEBS J., Vol. 274, Page 1849-, Year 2007
Publish dateAug 28, 2006 (structure data deposition date)
AuthorsFrasco, M.F. / Colletier, J. / Weik, M. / Carvalho, F. / Guilhermino, L. / Stojan, J. / Fournier, D.
External linksFEBS J. / PubMed:17355286
MethodsX-ray diffraction
Resolution2.75 Å
Structure data

PDB-2j4c:
Structure of human Butyrylcholinesterase in complex with 10mM HgCl2
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CL:
Unknown entry

ChemComp-HG:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-BUA:
butanoic acid

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / INHIBITION / GLYCOPROTEIN / POLYMORPHISM / INORGANIC MERCURY / CHOLINESTERASE / SERINE ESTERASE / DISEASE MUTATION

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