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-Structure paper
| Title | Crystal structure of the T877A human androgen receptor ligand-binding domain complexed to cyproterone acetate provides insight for ligand-induced conformational changes and structure-based drug design. |
|---|---|
| Journal, issue, pages | J. Biol. Chem., Vol. 282, Page 13648-13655, Year 2007 |
| Publish date | Feb 25, 2007 (structure data deposition date) |
Authors | Bohl, C.E. / Wu, Z. / Miller, D.D. / Bell, C.E. / Dalton, J.T. |
External links | J. Biol. Chem. / PubMed:17311914 |
| Methods | X-ray diffraction |
| Resolution | 1.8 Å |
| Structure data | ![]() PDB-2oz7: |
| Chemicals | ![]() ChemComp-CA4: ![]() ChemComp-HOH: |
| Source |
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Keywords | HORMONE RECEPTOR / androgen receptor / anti-androgen / prostate cancer |
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homo sapiens (human)
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