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TitleStructure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 14, Page 229-233, Year 2007
Publish dateApr 7, 2006 (structure data deposition date)
AuthorsTarendeau, F. / Boudet, J. / Guilligay, D. / Mas, P.J. / Bougault, C.M. / Boulo, S. / Baudin, F. / Ruigrok, R.W. / Daigle, N. / Ellenberg, J. ...Tarendeau, F. / Boudet, J. / Guilligay, D. / Mas, P.J. / Bougault, C.M. / Boulo, S. / Baudin, F. / Ruigrok, R.W. / Daigle, N. / Ellenberg, J. / Cusack, S. / Simorre, J.P. / Hart, D.J.
External linksNat. Struct. Mol. Biol. / PubMed:17310249
MethodsNMR (solution) / X-ray diffraction
Resolution2.2 Å
Structure data

PDB-2gmo:
NMR-structure of an independently folded C-terminal domain of influenza polymerase subunit PB2
Method: SOLUTION NMR

PDB-2jdq:
C-terminal domain of influenza A virus polymerase PB2 subunit in complex with human importin alpha5
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • influenza a virus (a/victoria/3/1975(h3n2))
  • homo sapiens (human)
  • influenza a virus
KeywordsVIRAL PROTEIN / compact beta-structure / PROTEIN TRANSPORT / TRANSPORT / PB2 SUBUNIT / NUCLEAR PROTEIN / ARMADILLO REPEATS / INFLUENZA A VIRUS RNA-DEPENDENT RNA POLYMERASE / BIPARTITE NUCLEAR LOCALISATION SIGNAL / NUCLEAR IMPORT ADAPTER / HUMAN IMPORTIN ALPHA5 / HOST-VIRUS INTERACTION

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