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TitleCompetitive Inhibitors of the CphA Metallo-{beta}-Lactamase from Aeromonas hydrophila
Journal, issue, pagesAntimicrob. Agents Chemother., Vol. 51, Page 2136-2142, Year 2007
Publish dateApr 3, 2006 (structure data deposition date)
AuthorsHorsfall, L.E. / Garau, G. / Lienard, B.M.R. / Dideberg, O. / Schofield, C.J. / Frere, J.M. / Galleni, M.
External linksAntimicrob. Agents Chemother. / PubMed:17307979
MethodsX-ray diffraction
Resolution1.86 Å
Structure data

PDB-2gkl:
Crystal structure of the zinc carbapenemase CPHA in complex with the inhibitor pyridine-2,4-dicarboxylate
Method: X-RAY DIFFRACTION / Resolution: 1.86 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-PD2:
PYRIDINE-2,4-DICARBOXYLIC ACID

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • aeromonas hydrophila (bacteria)
KeywordsHYDROLASE / LACTAMASE / INHIBITOR / ZN

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