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Structure paper

TitleCrystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution.
Journal, issue, pagesJ. Virol., Vol. 81, Page 4753-, Year 2007
Publish dateOct 17, 2006 (structure data deposition date)
AuthorsYap, T.L. / Xu, T. / Chen, Y.L. / Malet, H. / Egloff, M.P. / Canard, B. / Vasudevan, S.G. / Lescar, J.
External linksJ. Virol. / PubMed:17301146
MethodsX-ray diffraction
Resolution1.85 - 2.6 Å
Structure data

PDB-2j7u:
Dengue virus NS5 RNA dependent RNA polymerase domain
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-2j7w:
Dengue virus NS5 RNA dependent RNA polymerase domain complexed with 3' dGTP
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-HOH:
WATER

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

Source
  • dengue virus
KeywordsVIRAL PROTEIN / NUCLEOSIDE BINDING SITE / FLAVIVIRUS / HIGH-THROUGHPUT ASSAY / RNA-DEPENDENT RNA POLYMERASE / DENGUE

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