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-Structure paper
Title | Design, Synthesis, and Crystal Structure of Hydroxyethyl Secondary Amine-Based Peptidomimetic Inhibitors of Human beta-Secretase. |
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Journal, issue, pages | J. Med. Chem., Vol. 50, Page 776-781, Year 2007 |
Publish date | Oct 13, 2006 (structure data deposition date) |
Authors | Maillard, M.C. / Hom, R.K. / Benson, T.E. / Moon, J.B. / Mamo, S. / Bienkowski, M. / Tomasselli, A.G. / Woods, D.D. / Prince, D.B. / Paddock, D.J. ...Maillard, M.C. / Hom, R.K. / Benson, T.E. / Moon, J.B. / Mamo, S. / Bienkowski, M. / Tomasselli, A.G. / Woods, D.D. / Prince, D.B. / Paddock, D.J. / Emmons, T.L. / Tucker, J.A. / Dappen, M.S. / Brogley, L. / Thorsett, E.D. / Jewett, N. / Sinha, S. / John, V. |
External links | J. Med. Chem. / PubMed:17300163 |
Methods | X-ray diffraction |
Resolution | 1.7 Å |
Structure data | PDB-2iqg: |
Chemicals | ChemComp-F2I: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / protein-inhibitor complex |