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TitleA structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 104, Page 814-818, Year 2007
Publish dateSep 6, 2006 (structure data deposition date)
AuthorsAller, P. / Rould, M.A. / Hogg, M. / Wallace, S.S. / Doublie, S.
External linksProc. Natl. Acad. Sci. USA / PubMed:17210917
MethodsX-ray diffraction
Resolution2.65 Å
Structure data

PDB-2dy4:
Crystal structure of RB69 GP43 in complex with DNA containing Thymine Glycol
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • enterobacteria phage rb69 (virus)
KeywordsTRANSFERASE/DNA / DNA polymerase / DNA lesion / thymine glycol / oxidative thymine lesion / TRANSFERASE-DNA COMPLEX

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