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Structure paper

TitleDrug Export Pathway of Multidrug Exporter Acrb Revealed by Darpin Inhibitors.
Journal, issue, pagesPlos Biol., Vol. 5, Page E7-, Year 2007
Publish dateOct 27, 2006 (structure data deposition date)
AuthorsSennhauser, G. / Amstutz, P. / Briand, C. / Storchenegger, O. / Grutter, M.G.
External linksPlos Biol. / PubMed:17194213
MethodsX-ray diffraction
Resolution2.54 Å
Structure data

PDB-2j8s:
Drug Export Pathway of Multidrug Exporter AcrB Revealed by DARPin Inhibitors
Method: X-RAY DIFFRACTION / Resolution: 2.54 Å

Chemicals

ChemComp-LMT:
DODECYL-BETA-D-MALTOSIDE / detergent*YM

ChemComp-LMU:
DODECYL-ALPHA-D-MALTOSIDE / detergent*YM

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
  • synthetic construct (others)
KeywordsMEMBRANE PROTEIN / MEMBRANE PROTEIN-COMPLEX / DESIGNED ANKYRIN REPEAT PROTEIN / MULTIDRUG RESISTANCE PROTEIN / CO-CRYSTALLIZATION / ANTIBIOTIC RESISTANCE / INNER MEMBRANE / PROTEIN COMPLEX / RND / MEMBRANE / INHIBITOR / TRANSPORT / TRANSMEMBRANE / DRUG-EFFLUX PUMP / TRANSPORT PROTEIN / ANTIBIOTIC RESISTANCE-INHIBITOR COMPLEX

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