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Structure paper

Title3-Hydroxychromones as cyclin-dependent kinase inhibitors: synthesis and biological evaluation.
Journal, issue, pagesBioorg. Med. Chem. Lett., Vol. 17, Page 1284-1287, Year 2007
Publish dateJul 27, 2006 (structure data deposition date)
AuthorsLee, J. / Park, T. / Jeong, S. / Kim, K.H. / Hong, C.
External linksBioorg. Med. Chem. Lett. / PubMed:17178224
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-2duv:
Structure of CDK2 with a 3-hydroxychromones
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-371:
2-(3,4-DIHYDROXYPHENYL)-8-(1,1-DIOXIDOISOTHIAZOLIDIN-2-YL)-3-HYDROXY-6-METHYL-4H-CHROMEN-4-ONE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / protein kinase / serine/threonine-protein kinase / cell division

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