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-Structure paper
Title | Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 17, Page 688-691, Year 2007 |
Publish date | Oct 26, 2006 (structure data deposition date) |
![]() | Tari, L.W. / Hoffman, I.D. / Bensen, D.C. / Hunter, M.J. / Nix, J. / Nelson, K.J. / McRee, D.E. / Swanson, R.V. |
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Methods | X-ray diffraction |
Resolution | 2.25 Å |
Structure data | ![]() PDB-2np8: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-CC3: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / Aurora A kinase / AIK / aurora 2 kinase / kinase / kinase inhibitor |