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-Structure paper
Title | Demonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885. |
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Journal, issue, pages | Cancer Res., Vol. 66, Page 11100-11105, Year 2006 |
Publish date | Dec 8, 2005 (structure data deposition date) |
Authors | King, A.J. / Patrick, D.R. / Batorsky, R.S. / Ho, M.L. / Do, H.T. / Zhang, S.Y. / Kumar, R. / Rusnak, D.W. / Takle, A.K. / Wilson, D.M. ...King, A.J. / Patrick, D.R. / Batorsky, R.S. / Ho, M.L. / Do, H.T. / Zhang, S.Y. / Kumar, R. / Rusnak, D.W. / Takle, A.K. / Wilson, D.M. / Hugger, E. / Wang, L. / Karreth, F. / Lougheed, J.C. / Lee, J. / Chau, D. / Stout, T.J. / May, E.W. / Rominger, C.M. / Schaber, M.D. / Luo, L. / Lakdawala, A.S. / Adams, J.L. / Contractor, R.G. / Smalley, K.S. / Herlyn, M. / Morrissey, M.M. / Tuveson, D.A. / Huang, P.S. |
External links | Cancer Res. / PubMed:17145850 |
Methods | X-ray diffraction |
Resolution | 2.9 Å |
Structure data | PDB-2fb8: |
Chemicals | ChemComp-215: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / kinase domain |