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-Structure paper
Title | Macrocyclic Aminopyrimidines as Multitarget Cdk and Vegf-R Inhibitors with Potent Antiproliferative Activities. |
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Journal, issue, pages | Chemmedchem, Vol. 2, Page 63-, Year 2007 |
Publish date | Nov 13, 2006 (structure data deposition date) |
Authors | Luecking, U. / Siemeister, G. / Schaefer, M. / Briem, H. / Krueger, M. / Lienau, P. / Jautelat, R. |
External links | Chemmedchem / PubMed:17131463 |
Methods | X-ray diffraction |
Resolution | 2.5 Å |
Structure data | PDB-2j9m: |
Chemicals | ChemComp-PY8: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / SERINE-THREONINE PROTEIN KINASE / SERINE/THREONINE-PROTEIN KINASE / NUCLEOTIDE-BINDING / ARYLAMINE N-ACETYLTRANSFERASE / CELL DIVISION / DRUG METABOLISM / PHOSPHORYLATION / ATP-BINDING / MYCOBACTERIA / NAT / KINASE / MITOSIS / ISONIAZID / CELL CYCLE |