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TitleCarbonic anhydrase activators: L-Adrenaline plugs the active site entrance of isozyme II, activating better isoforms I, IV, VA, VII, and XIV.
Journal, issue, pagesBioorg. Med. Chem. Lett., Vol. 17, Page 628-635, Year 2007
Publish dateJul 5, 2006 (structure data deposition date)
AuthorsTemperini, C. / Innocenti, A. / Scozzafava, A. / Mastrolorenzo, A. / Supuran, C.T.
External linksBioorg. Med. Chem. Lett. / PubMed:17127057
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-2hkk:
Carbonic anhydrase activators: Solution and X-ray crystallography for the interaction of andrenaline with various carbonic anhydrase isoforms
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HG:
Unknown entry

ChemComp-ALE:
L-EPINEPHRINE / medication, hormone*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLYASE / carbonic anhydrase / activators

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