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Structure paper

TitleStructural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.
Journal, issue, pagesJ. Biol. Chem., Vol. 282, Page 9182-9194, Year 2007
Publish dateOct 25, 2006 (structure data deposition date)
AuthorsRadom, C.T. / Banerjee, A. / Verdine, G.L.
External linksJ. Biol. Chem. / PubMed:17114185
MethodsX-ray diffraction
Resolution2.01 - 2.57 Å
Structure data

PDB-2nob:
Structure of catalytically inactive H270A human 8-oxoguanine glycosylase crosslinked to 8-oxoguanine DNA
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-2noe:
Structure of catalytically inactive G42A human 8-oxoguanine glycosylase complexed to 8-oxoguanine DNA
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-2nof:
Structure of Q315F human 8-oxoguanine glycosylase proximal crosslink to 8-oxoguanine DNA
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

PDB-2noh:
Structure of catalytically inactive Q315A human 8-oxoguanine glycosylase complexed to 8-oxoguanine DNA
Method: X-RAY DIFFRACTION / Resolution: 2.01 Å

PDB-2noi:
Structure of G42A human 8-oxoguanine glycosylase crosslinked to undamaged G-containing DNA
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

PDB-2nol:
Structure of catalytically inactive human 8-oxoguanine glycosylase distal crosslink to oxoG DNA
Method: X-RAY DIFFRACTION / Resolution: 2.57 Å

PDB-2noz:
Structure of Q315F human 8-oxoguanine glycosylase distal crosslink to 8-oxoguanine DNA
Method: X-RAY DIFFRACTION / Resolution: 2.43 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHydrolase / Lyase/DNA / N-glycosylase/DNA lyase / DNA repair / 8-oxoguanine / Lyase-DNA COMPLEX

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