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TitleInsights Into the Synthesis of Lipopolysaccharide and Antibiotics Through the Structures of Two Retaining Glycosyltransferases from Family Gt4
Journal, issue, pagesChem. Biol., Vol. 13, Page 1143-, Year 2006
Publish dateJun 8, 2006 (structure data deposition date)
AuthorsMartinez-Fleites, C. / Proctor, M. / Roberts, S. / Bolam, D.N. / Gilbert, H.J. / Davies, G.J.
External linksChem. Biol. / PubMed:17113996
MethodsX-ray diffraction
Resolution1.5 - 2.3 Å
Structure data

PDB-2iuy:
Crystal structure of AviGT4, a glycosyltransferase involved in Avilamycin A biosynthesis
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-2iv3:
Crystal structure of AviGT4, a glycosyltransferase involved in Avilamycin A biosynthesis
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-2iv7:
Crystal Structure of WaaG, a glycosyltransferase involved in lipopolysaccharide biosynthesis
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-2iw1:
Crystal Structure of WaaG, a glycosyltransferase involved in lipopolysaccharide biosynthesis
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-UDP:
URIDINE-5'-DIPHOSPHATE / UDP*YM

ChemComp-GOL:
GLYCEROL

ChemComp-U2F:
URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE

Source
  • streptomyces viridochromogenes (bacteria)
  • escherichia coli (E. coli)
KeywordsTRANSFERASE / GLYCOSYLTRANSFERASE / ANTIBIOTICS / FAMILY GT-4 / AVILAMYCIN A / LIPOPOLYSACCHARIDE BIOSYNTHESIS / LPS / RETAINING / UDP-GLUCOSE

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