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Structure paper

TitleSubstrate Specificity of a Metalloprotease of the Pappalysin Family Revealed by an Inhibitor and a Product Complex.
Journal, issue, pagesArch. Biochem. Biophys., Vol. 457, Page 57-, Year 2007
Publish dateOct 18, 2006 (structure data deposition date)
AuthorsGarcia-Castellanos, R. / Tallant, C. / Marrero, A. / Sola, M. / Baumann, U. / Gomis-Ruth, F.X.
External linksArch. Biochem. Biophys. / PubMed:17097044
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-2j83:
Ulilysin metalloprotease in complex with batimastat.
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-BAT:
4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE / inhibitor*YM

ChemComp-CA:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • methanosarcina acetivorans (archaea)
KeywordsHYDROLASE / IGFBP PROTEASE / METALLOPROTEASE / HYDROXAMATE INHIBITOR / CANCER / METZINCIN

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