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TitleA Ras-induced conformational switch in the Ras activator Son of sevenless.
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 103, Page 16692-16697, Year 2006
Publish dateSep 27, 2006 (structure data deposition date)
AuthorsFreedman, T.S. / Sondermann, H. / Friedland, G.D. / Kortemme, T. / Bar-Sagi, D. / Marqusee, S. / Kuriyan, J.
External linksProc. Natl. Acad. Sci. Usa / PubMed:17075039
MethodsX-ray diffraction
Resolution2.02 - 2.2 Å
Structure data

PDB-2ii0:
Crystal Structure of catalytic domain of Son of sevenless (Rem-Cdc25) in the absence of Ras
Method: X-RAY DIFFRACTION / Resolution: 2.02 Å

PDB-2ije:
Crystal Structure of the Cdc25 domain of RasGRF1
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsSIGNALING PROTEIN / RasGRF1 / Cdc25 Domain / Ras Guanine Nucleotide Releasing Factor / Ras-specific Nucleotide Exchange Factor

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