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TitleMechanism of Intracellular Block of the KcsA K(+) Channel by Tetrabutylammonium: Insights from X-ray Crystallography, Electrophysiology and Replica-exchange Molecular Dynamics Simulations.
Journal, issue, pagesJ. Mol. Biol., Vol. 365, Page 649-662, Year 2007
Publish dateJun 30, 2006 (structure data deposition date)
AuthorsFaraldo-Gomez, J.D. / Kutluay, E. / Jogini, V. / Zhao, Y. / Heginbotham, L. / Roux, B.
External linksJ. Mol. Biol. / PubMed:17070844
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-2hjf:
Potassium channel kcsa-fab complex with tetrabutylammonium (TBA)
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-K:
Unknown entry

ChemComp-TBA:
TETRABUTYLAMMONIUM ION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • streptomyces lividans (bacteria)
KeywordsMETAL TRANSPORT / Potassium Channel / Ion transport

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