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TitleEnhanced major histocompatibility complex class I binding and immune responses through anchor modification of the non-canonical tumour-associated mucin 1-8 peptide
Journal, issue, pagesImmunology, Vol. 119, Page 306-316, Year 2006
Publish dateJan 12, 2006 (structure data deposition date)
AuthorsLazoura, E. / Lodding, J. / Farrugia, W. / Ramsland, P.A. / Stevens, J. / Wilson, I.A. / Pietersz, G.A. / Apostolopoulos, V.
External linksImmunology / PubMed:17067310
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-2fo4:
Enhanced MHC class I binding and immune responses through anchor modification of the non-canonical tumor associated MUC1-8 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-PO4:
PHOSPHATE ION

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / anchor modifications / H-2Kb / MUC1 / non-canonical peptide / MUC1-8 / vaccine design

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