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-Structure paper
Title | Slow-onset inhibition of fumarylacetoacetate hydrolase by phosphinate mimics of the tetrahedral intermediate: kinetics, crystal structure and pharmacokinetics. |
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Journal, issue, pages | Biochem. J., Vol. 402, Page 251-260, Year 2007 |
Publish date | Aug 9, 2006 (structure data deposition date) |
![]() | Bateman, R.L. / Ashworth, J. / Witte, J.F. / Baker, L.J. / Bhanumoorthy, P. / Timm, D.E. / Hurley, T.D. / Grompe, M. / McClard, R.W. |
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Methods | X-ray diffraction |
Resolution | 1.35 Å |
Structure data | ![]() PDB-2hzy: |
Chemicals | ![]() ChemComp-NA: ![]() ChemComp-MN: ![]() ChemComp-CA: ![]() ChemComp-NI: ![]() ChemComp-DHJ: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / transition-state mimicking complex |