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Structure paper

TitleA Mutation in the S-Switch Region of the Runt Domain Alters the Dynamics of an Allosteric Network Responsible for Cbfbeta Regulation.
Journal, issue, pagesJ. Mol. Biol., Vol. 364, Page 1073-, Year 2006
Publish dateOct 4, 2006 (structure data deposition date)
AuthorsLi, Z. / Lukasik, S.M. / Liu, Y. / Grembecka, J. / Bielnicka, I. / Bushweller, J.H. / Speck, N.A.
External linksJ. Mol. Biol. / PubMed:17059830
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-2j6w:
R164N mutant of the RUNX1 Runt domain
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsTRANSCRIPTION / TRANSCRIPTION FACTOR / TRANSCRIPTION/DNA / CHLORIDE BINDING / ACUTE MYELOID LEUKEMIA / TRANSCRIPTION REGULATION / NUCLEAR PROTEIN / PHOSPHORYLATION / AML / RUNX1 / IG FOLD / RUNT DOMAIN / DNA-BINDING

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