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Structure paper

TitleStructural and Biochemical Analysis of the Rv0805 Cyclic Nucleotide Phosphodiesterase from Mycobacterium tuberculosis.
Journal, issue, pagesJ. Mol. Biol., Vol. 365, Page 211-225, Year 2007
Publish dateAug 4, 2006 (structure data deposition date)
AuthorsShenoy, A.R. / Capuder, M. / Draskovic, P. / Lamba, D. / Visweswariah, S.S. / Podobnik, M.
External linksJ. Mol. Biol. / PubMed:17059828
MethodsX-ray diffraction
Resolution1.932 - 2.25 Å
Structure data

PDB-2hy1:
Crystal structure of Rv0805
Method: X-RAY DIFFRACTION / Resolution: 1.932 Å

PDB-2hyo:
Crystal structure of Rv0805 N97A mutant
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-2hyp:
Crystal structure of Rv0805 D66A mutant
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-FE:
Unknown entry

ChemComp-MN:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

ChemComp-BR:
BROMIDE ION

ChemComp-CAC:
CACODYLATE ION

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsHYDROLASE / metallophosphoesterase / cAMP / phosphodiesterase / bi-nuclear active site

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