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-Structure paper
Title | Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of 5-amino-1,3,4-thiadiazole-2-sulfonamide and 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)-1,3,4-thiadiazole-2-sulfonamide to human isoform II. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 16, Page 6204-6208, Year 2006 |
Publish date | Jul 12, 2006 (structure data deposition date) |
Authors | Menchise, V. / De Simone, G. / Di Fiore, A. / Scozzafava, A. / Supuran, C.T. |
External links | Bioorg. Med. Chem. Lett. / PubMed:17000110 |
Methods | X-ray diffraction |
Resolution | 1.55 - 2.1 Å |
Structure data | PDB-2hnc: PDB-2hoc: |
Chemicals | ChemComp-ZN: ChemComp-1SA: ChemComp-MBO: ChemComp-GOL: ChemComp-HOH: ChemComp-1CN: |
Source |
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Keywords | LYASE / Protein-inhibitor complex |