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Structure paper

TitleCrystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site.
Journal, issue, pagesJ. Mol. Biol., Vol. 362, Page 1094-1107, Year 2006
Publish dateOct 20, 2005 (structure data deposition date)
AuthorsDebela, M. / Magdolen, V. / Grimminger, V. / Sommerhoff, C. / Messerschmidt, A. / Huber, R. / Friedrich, R. / Bode, W. / Goettig, P.
External linksJ. Mol. Biol. / PubMed:16950394
MethodsX-ray diffraction
Resolution1.95 - 3 Å
Structure data

PDB-2bdg:
Human Kallikrein 4 complex with nickel and p-aminobenzamidine
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-2bdh:
Human Kallikrein 4 complex with zinc and p-aminobenzamidine
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-2bdi:
Human Kallikrein 4 complex with cobalt and p-aminobenzamidine
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-NI:
NICKEL (II) ION

ChemComp-PBZ:
P-AMINO BENZAMIDINE

ChemComp-HOH:
WATER

ChemComp-ZN:
Unknown entry

ChemComp-CO:
Unknown entry

Source
  • homo sapiens (human)
KeywordsHYDROLASE / serine proteinase / s1 subsite / 70-80 loop / Structural Proteomics in Europe / SPINE / Structural Genomics

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