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Structure paper

TitleDiabetes mellitus due to misfolding of a beta-cell transcription factor: stereospecific frustration of a Schellman motif in HNF-1alpha.
Journal, issue, pagesJ. Mol. Biol., Vol. 362, Page 414-429, Year 2006
Publish dateMay 9, 2006 (structure data deposition date)
AuthorsNarayana, N. / Phillips, N.B. / Hua, Q.X. / Jia, W. / Weiss, M.A.
External linksJ. Mol. Biol. / PubMed:16930618
MethodsX-ray diffraction
Resolution1.4 Å
Structure data

PDB-2gyp:
Diabetes mellitus due to a frustrated Schellman motif in HNF-1a
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-HOH:
WATER

KeywordsTRANSCRIPTION REGULATOR / energy landscape / gene regulation / protein engineering / protein stability / protein structure

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