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TitleBiosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase.
Journal, issue, pagesNat. Chem. Biol., Vol. 2, Page 494-502, Year 2006
Publish dateJun 6, 2006 (structure data deposition date)
AuthorsAustin, M.B. / Saito, T. / Bowman, M.E. / Haydock, S. / Kato, A. / Moore, B.S. / Kay, R.R. / Noel, J.P.
External linksNat. Chem. Biol. / PubMed:16906151
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-2h84:
Crystal Structure of the C-terminal Type III Polyketide Synthase (PKS III) Domain of 'Steely1' (a Type I/III PKS Hybrid from Dictyostelium)
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-P6G:
HEXAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • dictyostelium discoideum (eukaryote)
KeywordsBIOSYNTHETIC PROTEIN / TRANSFERASE / thiolase-fold / type III polyketide synthase / PKS / chalcone-stilbene synthase superfamily / type I PKS / type I fatty acid synthase / FAS

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