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TitleCrystal Structure of Visfatin/Pre-B Cell Colony-enhancing Factor 1/Nicotinamide Phosphoribosyltransferase, Free and in Complex with the Anti-cancer Agent FK-866
Journal, issue, pagesJ. Mol. Biol., Vol. 362, Page 66-77, Year 2006
Publish dateMar 5, 2006 (structure data deposition date)
AuthorsKim, M.-K. / Lee, J.H. / Kim, H. / Park, S.J. / Kim, S.H. / Kang, G.B. / Lee, Y.S. / Kim, J.B. / Kim, K.K. / Suh, S.W. / Eom, S.H.
External linksJ. Mol. Biol. / PubMed:16901503
MethodsX-ray diffraction
Resolution1.9 - 2.9 Å
Structure data

PDB-2g95:
Crystal Structure of Visfatin/Pre-B Cell Colony Enhancing Factor 1/Nicotinamide Phosphoribosyltransferase
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2g96:
Crystal Structure of Visfatin/Pre-B Cell Colony Enhancing Factor 1/Nicotinamide Phosphoribosyltransferase In Complex with Niconamide Mononucleotide
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-2g97:
Crystal Structure of Visfatin/Pre-B Cell Colony Enhancing Factor 1/Nicotinamide Phosphoribosyltransferase In Complex with the Specific Inhibitor FK-866
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NMN:
BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE

ChemComp-DGB:
(2E)-N-{4-[1-(benzenecarbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide

Source
  • rattus norvegicus (Norway rat)
KeywordsTRANSFERASE / Visfatin / PBEF / NAmPRTase / Rattus norvegicus / nmn / FK-866

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