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-Structure paper
Title | Synthesis of bicyclic molecular scaffolds (BTAa): an investigation towards new selective MMP-12 inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 14, Page 7392-7403, Year 2006 |
Publish date | Jul 26, 2006 (structure data deposition date) |
![]() | Mannino, C. / Nievo, M. / Machetti, F. / Papakyriakou, A. / Calderone, V. / Fragai, M. / Guarna, A. |
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Methods | X-ray diffraction |
Resolution | 1.32 Å |
Structure data | ![]() PDB-2hu6: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-CA: ![]() ChemComp-37A: ![]() ChemComp-HAE: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / MMP-12 / matrix metalloproteinase / macrophage metalloelastase / inhibitor / hydroxamic acid / drug design |