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TitleSiglec-7 Undergoes a Major Conformational Change When Complexed with the {alpha}(2,8)-Disialylganglioside GT1b
Journal, issue, pagesJ. Biol. Chem., Vol. 281, Page 32774-32783, Year 2006
Publish dateJul 20, 2006 (structure data deposition date)
AuthorsAttrill, H. / Imamura, A. / Sharma, R.S. / Kiso, M. / Crocker, P.R. / van Aalten, D.M.F.
External linksJ. Biol. Chem. / PubMed:16895906
MethodsX-ray diffraction
Resolution1.85 Å
Structure data

PDB-2hrl:
Siglec-7 in complex with GT1b
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CEQ:
ETHYL-TRIMETHYL-SILANE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCELL ADHESION / Ig-like domain / Siglec / Ganglioside / Siglec-7

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