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Structure paper

TitleStructural basis for induced-fit binding of Rho-kinase to the inhibitor Y-27632
Journal, issue, pagesJ. Biochem. (Tokyo), Vol. 140, Page 305-311, Year 2006
Publish dateJun 12, 2006 (structure data deposition date)
AuthorsYamaguchi, H. / Miwa, Y. / Kasa, M. / Kitano, K. / Amano, M. / Kaibuchi, K. / Hakoshima, T.
External linksJ. Biochem. (Tokyo) / PubMed:16891330
MethodsX-ray diffraction
Resolution3.1 Å
Structure data

PDB-2h9v:
Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y27632
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-Y27:
(R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE

ChemComp-HOH:
WATER

Source
  • bos taurus (domestic cattle)
KeywordsTRANSFERASE / protein kinase-inhibitor complex

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