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Structure paper

TitleStructural Basis for Corest-Dependent Demethylation of Nucleosomes by the Human Lsd1 Histone Demethylase
Journal, issue, pagesMol. Cell, Vol. 23, Page 377-, Year 2006
Publish dateJun 26, 2006 (structure data deposition date)
AuthorsYang, M. / Gocke, C.B. / Luo, X. / Borek, D. / Tomchick, D.R. / Machius, M. / Otwinowski, Z. / Yu, H.
External linksMol. Cell / PubMed:16885027
MethodsX-ray diffraction
Resolution2.57 Å
Structure data

PDB-2iw5:
Structural Basis for CoREST-Dependent Demethylation of Nucleosomes by the Human LSD1 Histone Demethylase
Method: X-RAY DIFFRACTION / Resolution: 2.57 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-CL:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-NH4:
AMMONIUM ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE/TRANSCRIPTION REGULATOR / OXIDOREDUCTASE-TRANSCRIPTION REGULATOR COMPLEX / OXIDOREDUCTASE-REPRESSOR COMPLEX / HISTONE DEMETHYLASE / FAD / LSD1 / COREST / REPRESSOR / TRANSCRIPTION REGULATION / HOST-VIRUS INTERACTION / CHROMATIN DEMETHYLATION / NUCLEAR PROTEIN / PHOSPHORYLATION / CHROMATIN REGULATOR / NUCLEOSOMES / TRANSCRIPTION / OXIDOREDUCTASE

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