Movie
Controller
Structure viewers
About Yorodumi Papers
+Search query
-Structure paper
| Title | Novel 2-Aminopyrimidine Carbamates as Potent and Orally Active Inhibitors of Lck: Synthesis, SAR, and in Vivo Antiinflammatory Activity |
|---|---|
| Journal, issue, pages | J. Med. Chem., Vol. 49, Page 4981-, Year 2006 |
| Publish date | Jan 4, 2007 (structure data deposition date) |
 Authors | Martin, M.W. / Newcomb, J. / Nunes, J.J. / McGowan, D.C. / Armistead, D.M. / Boucher, C. / Buchanan, J.L. / Buckner, W. / Chai, L. / Elbaum, D. ...Martin, M.W. / Newcomb, J. / Nunes, J.J. / McGowan, D.C. / Armistead, D.M. / Boucher, C. / Buchanan, J.L. / Buckner, W. / Chai, L. / Elbaum, D. / Epstein, L.F. / Faust, T. / Flynn, S. / Gallant, P. / Gore, A. / Gu, Y. / Hsieh, F. / Huang, X. / Lee, J.H. / Metz, D. / Middleton, S. / Mohn, D. / Morgenstern, K. / Morrison, M.J. / Novak, P.M. / Oliveira-dos-Santos, A. / Powers, D. / Rose, P. / Schneider, S. / Sell, S. / Tudor, Y. / Turci, S.M. / Welcher, A.A. / White, R.D. / Zack, D. / Zhao, H. / Zhu, L. / Zhu, X. / Ghiron, C. / Amouzegh, P. / Ermann, M. / Jenkins, J. / Johnston, D. / Napier, S. / Power, E. |
 External links | J. Med. Chem. / PubMed:16884310 |
| Methods | X-ray diffraction |
| Resolution | 2 Å |
| Structure data |  PDB-2ofu: |
| Chemicals |  ChemComp-SO4:  ChemComp-1N9:  ChemComp-HOH: |
| Source |
|
 Keywords | TRANSFERASE / Lck / Kinase domain |
homo sapiens (human)